Thomas M. Laue

Professor of Biochemistry and Molecular Biology
University of New Hampshire
Durham, NH 03824-3544
603.862.3544 (voice)
603.862.0031 (fax)
Tom.Laue@unh.com

EDUCATION
University of Connecticut	Biophysics and Biochemistry	PhD 1981
The Johns Hopkins University	Natural Sciences	BA 1973
APPOINTMENTS
Professor, University of New Hampshire, Durham, NH		1996-Present
Director, Biomolecular Interaction Technologies Center		2001-Present
Director, Center to Advance Molecular Interaction Sciences		1999-Present
Member, Material Sciences Program, University of New Hampshire		2000-Present
Adjunct Professor, University of Connecticut		2000-Present
Chair, Biochemistry and Molecular Biology		1995-1997
Interim Chair, Biochemistry and Molecular Biology		1993-1994
Associate Professor, University of New Hampshire, Durham, NH		1989-1995
Assistant Professor, University of New Hampshire, Durham, NH		1984-1989
PRIMARY TEACHING RESPONSIBILITY
Biophysical Chemistry (BCHM 750/850)
Biochemistry (BCHM 658)
Polymer Characterization (MS 955)
Macromolecular Interactions (BCHM 950)
CURRENT GRADUATE RESEARCH ADVISEES (21 MS and PhD advisees)
Carrie Ann May (Ph.D. Candidate, Biochemistry and Molecular Biology)
Judith Gamble (Ph.D. Candidate, Biochemistry and Molecular Biology)
Bradley Langhorst (Ph.D. Candidate, Biochemistry and Molecular Biology)
Jason Welch (MS Candidate, Material Sciences)
SELECTED PUBLICATIONS (since 2000)
Moody TP, Kingsbury JS, Durant JA, Wilson TJ, Chase SF, Laue TM. (2005) "Valence and anion binding of bovine ribonuclease A between pH 6 and 8." Anal. Biochem. 336, 243-252.
Jiang S, Jacobs A, Laue TM, Caffrey M. (2004) "Solution structure of the coxsackievirus and adenovirus receptor domain 1." Biochemistry, 43,1847-53.
Bou-Abdallah F, Adinolfi S, Pastore A, Laue TM, Dennis Chasteen N. (2004) "Iron binding and oxidation kinetics in frataxin CyaY of Escherichia coli." J Mol Biol. 341, 605-15.
MacGregor, IK, Anderson AL, Laue TM (2004) "Fluorescence Detection for the XLI Ultracentrifuge" Biophys. Chem, 108, 165-185.
Chahla M, Wooll J, Laue TM, Nguyen N, Senear DF (2003) "Role of Protein-Protein Bridging Interactions on Cooperative Assembly of DNA-Bound CRP-CytR-CRP Complex and Regulation of the Escherichia Coli CytR Regulon." Biochemistry, 42, 3812-3825.
Durant JA, Chen C, Laue TM, Moody TP, Allison, SA (2002) "Use of T4 Lysozyme Charge Mutants to Examine Electrophoretic Models" Biophysical Chemistry, 101 102 593 609.
Lukasik SM, Zhang LN, Corpora T, Tomanicek S, Li YH, Kundu M, Hartman K, Liu PP, Laue TM, Biltonen RL, Speck NA, Bushweller JH, (2002) "Altered affinity of CBF beta SMMHC for Runx1 explains its role in leukemogenesis" Nature Structural Biology, 9, 674 679.
Zhao, G., Ceci, P., Ilan, A., Giangiacomo, L., Laue, T.M., Chiancone, E., and Chasteen, N.D. (2002) "Iron and Hydrogen Peroxide Detoxification Properties of Dps: A Ferritin-like DNA Binding Protein of Escherichia coli." Journal of Biological Chemistry 277, 27689-27696.
Grady, J.K., Zang, J., Laue, T.M., Arosio, P. and Chasteen, N. D. (2002) "Characterization of the H and L Subunit Ratios of Ferritins by SDS Capillary Gel Electrophoresis" 302, 263 268.
Liparoto, S.F., Myszka, D.G., Wu, Z. Goldstein, B., Laue, T.M. , and Ciardelli, T.L., (2002) "Analysis of the Role of the Interleukin-2 Receptor ? Chain in Ligand Binding" Biochemistry, 41, 2543-2551.
Arcidiacono, S., Mello, C., Butler, M., Welsh, E., Soares, J., Allen, A., Ziegler, D., Laue, T. and Chase, S. (2002) "Aqueous Processing and Fiber Spinning of Recombinant Spider Silks" Macromolecules, 35, 1262-1266.
Hattan S., Laue, T.M. and Chasteen, D.C., (2001) "Purification and characterization of a novel calcium binding protein from the extrapallial fluid of mollusc Mytilus edulis" Journal of Biological Chemistry, 276, 4461-4468.
Laue, T.M. (2001) "Sedimentation" in Encyclopedia of Life Sciences, www.els.net Kar, S.R., Kingsbury, J.S., Lewis, M.S., Laue, T.M. and Schuck, P. (2000) "Analysis of Transport Experiments using Pseudo-absorbance Data" Analytical Biochemistry, 285, 135-142.
SELECTED RECENT SERVICE ACTIVITIES
Editorial board- Journal of Biological Chemistry		2005-
Chair, University of New Hampshire Faculty Senate		2003-2004
Vice-chair, University of New Hampshire Faculty Senate		2002-2003
College Promotion and Tenure Committee (chair, 2003)		2001-2004
College Planning Commission (chair 1995)		1994-1996
Instructor, New Hampshire Science and Math Teachers Association, Exeter, New Hampshire		2003-2004
Speaker, Active Retirement Association, Durham, NH		2001-2004
Organizer and chair, First Gordon Research Conference on Reversible Associations in Structural and Molecular Biology		2000
Instructor, Analytical Ultracentrifugation Theory and Practice, Au Trans, France		2003
Instructor "Analytical Ultracentrifugation", NSF-sponsored workshop University of Connecticut		1992-Present